ľ�ϸ��Ӱ��

RM PhD Graduates

Congratulations to all of our graduates!

We are very proud of all of the amazing research conducted within the RMU. Here we showcase the work of our graduates, hoping to inspire the researchers of tomorrow.

2025 PhD Graduates

Innovative Strategies to Enable Prime Editing of PLN R14del-induced Cardiomyopathy
Yao Bing
Exploring New Territories In Perinatal Stroke: Brain Development, Functional Impact & Neuroregenerative Therapies
Lisanne Baak
Precision medicine for rare CFTR variants in people with Cystic Fibrosis
Marlou Bierlaagh
Novel 3D vascular disease models: Implications for the treatment of cardiovascular and renal diseases
Ranganath Maringanti
Ex Situ Heart Perfusion as a Platform for Therapeutic Intervention: An Experimental Journey
Mats Vervoorn
Shaping the kidney: Engineering advanced in vitro models for studying renal function in health and disease
Marta García Valverde
Advancements in Leg Malalignment Imaging
Chien Nguyen
Gene Correction on a Roll
Indy Joore
Lipid Nanoparticle-Mediated mRNA Delivery to the Heart From Bench to Preclinical Models
Clara Labonia
The Power of Springs to Treat Scoliosis
Justin Lemans
Dynamics in Total Hip Arthroplasty
Joost van Erp
Towards Perfect Acetabular Cup Placement in Total Hip Arthroplasty
Thom Snijders
It’s all about the horse… Or is it? Exploring the human side of equine veterinary practice
Yteke Elte
Advancing in vitro models of human cardiac fibrosis: Manipulating mechanotransduction
Tom Bracco Gartner
Advancing stem cell-based technologies for intervertebral disc regeneration: Exploring biology-driven cues to improve iPSCs differentiation toward notochordal-like cells
Xiaole Tong
Breaking the Vicious Circle of Nucleus Pulposus Degeneration: Exploring Advanced Treatment Options for Lower Back Pain
Lisanne Laagland
From Organoids to Bioprinting: Advancing the Building Blocks of Breast Tissue Engineering
Maj-Britt Buchholz
Heart Perfusion for Tailored Preservation and Regeneration: Innovative Techniques in the Surgical Treatment of Advanced Heart Failure
Selma Kaffka genaamd Dengler
A functional approach to articular cartilage repair with a critical note on animal experimentation
Maria Fugazzola
Transcriptional Diversity of Regulatory T Cells in Colorectal Cancer
Sonia Aristín Revilla

2024 PhD Graduates

WNT-mediated regulation of regeneration and oncogenesis
Joep Sprangers
Optimizing In Vitro Nasal Epithelial Cell Models for Enhanced Cilia-Related Airway Research
Hetty Dreyer
Clinical Translational Aspects in Regeneration: From Bench to Bone
Leanne DeSilva
Regulation of progenitor properties and tissue dysfunction by cellular senescence
Thomas Brand
Advanced Imaging Techniques for Knee and Ankle Pathologies: Applications of Deep Learning and Statistical Shape Modelling
Saeed Arbabi
The potential of protein-bound uremic toxins as biomarkers of kidney tubular function
Sabbir Ahmed
Innovative in vitro platforms for investigating therapeutic effects and bio-distribution of extracellular vesicles: Towards Animal-Free Kidney Disease Modelling
Vivian Nguyen
CD4+ and CD8+ T cell behavior in the landscape of intestinal damage
Alessandro Cutilli
Maturation of the spine and its consequences for conservative treatment of adolescent idiopathic scoliosis
Lorenzo Costa
Alternatives to animal research: from in vitro to ex vivo liver models
Melanie Krüger
A context-based approach to unravel Variants of (Uncertain) Significance
Irena Muffels
Merging Macro and Micro: Transcriptional landscapes and in-depth studies for understanding heart disease
Louk Timmer
Endometrium-related infertility: molecular and clinical insights
Bich Bui
The Regenerating Body: An ethical analysis of personalized regenerative implants
Manon van Daal
Newborn screening for long-chain fatty acid oxidation disorders: Facing the challenges
Marit Schwantje
The heart of the matter: An ethical exploration of regenerative implants
Anne-Floor de Kanter
Periprosthetic joint infections: Development of new therapies
Bruce van Dijk
Silk fibroin in regenerative medicine: material evolution and biofabrication techniques
Martina Viola
New Methods to Monitor Kidney Function and Damage
Tobias Pieters
Navigating Vascular Complexity: Insights From hiPSC-derived vascular cells to Advanced 3D Models
Elana Meijer
Chronic Limb-Threatening Ischemia: Redefining the landscape
Joep Wijnand
Potentials of stem cell-derived cardiomyocytes - ‘From disease modeling to therapeutic strategies’
Renée Maas
Immunomodulatory Pathogen Recognition Receptor Ligands for Bone Regeneration
Paree Khokhani
Molecular and functional characterisation of rare CFTR variants
Juliet Lefferts
Articular cartilage-derived progenitor cells for cartilage tissue engineering - Advancing their potential towards the clinical translation for cartilage repair
Florencia Abinzano
Nasal epithelial cells as model for cystic fibrosis
Lisa Rodenburg
Crafting Tissue Complexity: Pioneering Layerwise and Volumetric Biofabrication Strategies for Advanced In Vitro Models
Paulina Nunez Bernal
Uncovering The Potential Of Proximal Tubule Cells For Disease Modeling And Therapeutic Interventions
João Faria
Diels-Alder Hydrogels and Micelles for Ocular Drug Delivery: From Design to Preclinical Evaluation
Blessing Ilochonwu
Developments in Knee Distraction dedicated devices and implementation
Thjimen Struik

2023 PhD Graduates

A layered approach of response to treatment in Psoriasis and Psoriatic Arthritis - A Link to the JAKs
Nanette Vincken
Improving functionality of living tissue constructs by expanding the applicability of melt electrowriting- Three-dimensional tissue regeneration guided by biochemical and structural cues using converged (bio)fabrication technologies
Madison Ainsworth
Extracellular Vesicle Heterogeneity and its Translational Implications for Cardiac Repair
Simon van de Wakker
Bioengineering hepatic organoids - Development of an alternative model for liver toxicity
Manon Bouwmeester
Intrahepatic cholangiocyte organoids for bile-duct tissue engineering and disease modeling
Zhenguo Wang
The Modern Day Heracles: Patient-derived Liver Organoids to Model Rare Pediatric Liver Diseases
Vivian Lehmann
Epithelial injury in acute graft-versus-host disease of the gut
Suze Jansen
Towards Better Patient Journeys in Metastatic Spinal Disease
Floris van Tol
Towards a responsibilization of stem cell researchers - a bioethical inquiry
Lars Assen
Modeling metastatic colorectal cancer subtypes to improve therapeutic strategies
Emre Küçükköse
Insights into protein-bound uremic toxins in proximal tubule cell senescence and kidney fibrosis
Yi Yang
Cystic Fibrosis: a real-world challenge to predict individual outcomes
Danya Muilwijk
Scoliosis - a Universal Rotational (De)compensation of the Spine
Steven de Reuver
Therapeutic strategies to rescue damaged heart
Juntao Fang
Thumb Carpometacarpal Osteoarthritis: New insights & Treatment opportunities
Janna Ottenhoff
Saving private macrophage: Alternative therapeutic options for Staphylococcus aureus implant-associated infections
Leonardo Cecotto
Strategies for intervertebral disc regeneration
Jie Du
Intrinsic joint repair: development of targeted treatment of inflammation in osteoarthritis
Kelly Warmink
Towards 3D fabrication of MgP-based mechanically competent implants for bone regeneration
Nasim Golafshan
Uncovering the molecular mechanisms underlying arrhythmogenic cardiomyopathy using the CRISPR-toolbox
Sebastiaan van Kampen
Adaptive Translational Medicine Towards New Therapeutic Approaches For Metabolic Diseases
Gautam Kok
Engineering the (vascularized) Proximal Tubule, a Guide Towards Functionality
Anne Metje van Genderen
Postoperative skeletal pain: Development of non-opioid treatment strategies
Jasper Steverink
Computer-Assisted Osteotomy Planning: Medical imaging techniques for orthopaedic surgery
Ruurd Kuiper
Modeling the ocular surface with organoid technology
Marie Bannier Hélaouët
Epigenetic regulation of normal and aberrant myelopoiesis; a balancing act
Anita Govers
BIG DATA to understand BIG HEARTS - Unravelling the molecular mechanisms in hypertrophic cardiomyopathy
Maya Wright Clark

2022 PhD Graduates

E2F transcription factors: master controllers of genomic integrity throughout the cell cycle
Qingwu Liu
Gene drive technologies: navigating the ethical landscape
Nienke de Graeff
Medical 3D technology, from bench to bedside
Koen Willemsen
Enhancing bone regeneration by calcium phosphates with surface topography: A translational evaluation of synthetic bone graft substitutes
Luuk van Dijk
Transcription takes the wheel in the replication stress response the road to drug sensitivity and resistance
Jet Segeren
Clinical investigation of bone graft substitutes in spinal fusion: Insights from a randomized intrapatient controlled trial
Mechteld Lehr
Knee joint preservation: Strategies for tissue repair and regeneration
Jasmijn Korpershoek
Saving the Joint: Biological Strategies to Preserve Cartilage
Margot Rikkers
Targeting pro-survival cell signaling pathways in multiple myeloma personalized treatment for newly-diagnosed and relapsed-refractory patients
Ingrid Spaan
Modelling of a wide variety of disease using adult stem cell-derived organoids
Jelte van der Vaart
Steps towards a wearable artificial kidney: The development and validation of innovative strategies to improve dialysis
Maaike de Gelder
A joint effort: How dogs contribute and benefit from the “One medicine” approach to osteoarthritis
Michelle Teunissen
Osteoarthritis: Towards a progressive APPROACH
Eefje van Helvoort
Regulation of gene expression during oocycle matauration
Bo Yu
Circadian rhythms in heart failure
Sandra Crnko
Osteoarthritis: Getting the picture
Willem Paul Gielis
Protective and pathological remodeling in cardiac disease
Arwa Kohela
Reno-cardiovascular disease and regeneration: focus on interactions with the immune system
Merle Krebber

Earlier PhD Graduates

Reno-cardiovascular disease and regeneration: focus on interactions with the immune system
Merle M. Krebber
Go big or go home - Translational approaches to target ischemic heart failure
Evelyne Demkes
To repair the infarcted heart
Marijn Peters
Discovery of Tissue-Specific Functions of Atypical E2Fs in Cancer
Eva Moreno Iglesias
Diamond-Blackfan anemia & other hereditary red cell disorders: spotting phenotypes
Birgit van Dooijeweert
Knee joint distraction: moving forward
Mylène P. Jansen
Vascular cell and extracellular matrix interactions: implications for vascular regeneration and disease modeling
Christian G. M. van Dijk
The DUX4 cytotoxic cascade, and CRISPR mitigation methods
Ator Ashoti