Cellular Structural Biology of Fertilization

molecular architecture of mammalian sperm

The scientific interest of the group is in the molecular basis of fertilization.

Fertilization is a complex multi-step process with a complicated spatiotemporal pattern; it includes sperm-oocyte recognition, interaction and fusion. The molecular basis of mammalian fertilization is still considered a molecular enigma. To address the open questions in the field the group is applying a cellular structural biology approach.

The group combines biochemistry, biophysics and advanced cryo-electron microscopy to unravel the molecular basis of fertilization

Interested in this subject ? look at our Research Projects     

Would like to join our team? contact us at z.zeev@uu.nl

Follow us @tzviyazbm.bsky.social

 

Further reading: