PhD Defense: Silenced but not Silent: how heterochromatin promotes its maintenance and stability
PhD Defense of Marit Amber Elze van Bueren
Our DNA carries the blueprint of life, but it is not left unprotected. Instead, it is packaged into chromatin, which can be organized in a loose form (euchromatin) or a compact form (heterochromatin). This packaging not only regulates which genes are active, but also plays a key role in protecting and repairing our DNA. Heterochromatin, however, poses a special challenge: its repetitive nature makes it more difficult to repair DNA damage, increasing the risk of errors that can lead to cancer and other diseases.
- Start date and time
- End date and time
- Location
- PhD candidate
- Marit Amber Elze van Bueren
- Dissertation
- Silenced but not Silent: how heterochromatin promotes its maintenance and stability
- PhD supervisor(s)
- prof. dr. S.M.A. Lens
- Co-supervisor(s)
- dr. A. Janssen