I am a PhD candidate working at the Regenerative Medicine Centre Utrecht, where my research is focused on the development of bovine organoid systems as physiologically relevant in vitro models. These models, derived from bovine intestinal, hepatic, and mammary gland tissue, are used to investigate the uptake, metabolism, distribution, and excretion of feed components, veterinary pharmaceuticals, and environmental contaminants.
This work is embedded within the RAAK-PRO project, a multidisciplinary collaboration aiming to establish a generic kinetic modelling platform to predict the transfer of chemical substances from feed and medicinal sources to edible bovine products such as milk and meat. By combining organoid-based functional assays with kinetic modelling and extrapolation techniques, this platform will facilitate data-driven safety evaluations while contributing to the replacement of animal testing.
The overarching aim of my research is to enhance predictive toxicology and food safety assessment in the livestock sector, while supporting the transition toward more sustainable and ethically responsible scientific practices.