In my group we work on a broad range of subjects in the fields of soft-matter and biophysics. We study the self-organization of colloids, (block) polymers and proteins into various kinds of larger structures. Our approach is a combination of experiments and theoretical modeling based on statistical thermodynamics.
Recently we developed a model to explain cooperative transitions involving hydrophobic polyelectrolytes and lipid bilayer membranes, see the link to our PNAS paper
In our work on transcription regulation we investigate the influence of various factors on the level of transcription of well-defined genetic architectures. In parallel, we develop statistical thermodynamic models based on collaboration with colleagues at Caltech, see .
Find out how the so-called titration effect in transcription regulation facilitates self-sustained oscillations in a minimal genetic feedback loop
And, check out on 'colloidal viruses'!
Colloidal viruses
Genetic regulation with colleagues at Caltech
On the PNAS cover
Leeropdracht
Zelf-ordenende systemen