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Declarative memory enables reports of both factual, conceptual general knowledge and personal knowledge. This involves various brain areas, as we know for instance from cases of brain damaged patients. But what are the dynamic, interactive effects of blood flow disruptions on these types of knowledge? In this project a large neurological/ neuropsychological patient database will be used to achieve integration of multimodal imaging data (CT perfusion, structural CT/MRI, DTI) and cognitive observations. Patients will be retested on an extended memory test three months after first onset of cerebral impairments. This will allow us to capture the dynamics of abnormalities in the neuronal circuitry of memory after stroke, in particular declarative memory.