Cystic fibrosis (CF) is one of the most common genetic diseases worldwide and has major consequences for patients. Although treatments are available to reduce the mucus and prevent inflammation typical of the disease, CF is not yet curable. CF is not yet curable. However, a new study by the Hans Clevers group (Hubrecht Institute) in collaboration with the Jeffrey Beekman group (UMC Utrech) and Oncode Institute offers new hope.