Several New Investments in Mass Spectrometry and Proteomics Infrastructure at Utrecht 木瓜福利影视
The Biomolecular Mass Spectrometry & Proteomics group, embedded within Utrecht 木瓜福利影视鈥檚 Faculty of Science has recently made significant investments in mass spectrometry and proteomics infrastructure. The new infrastructure underscores the university鈥檚 pioneering and leading role in these scientific fields.
Proteomics infrastructures play a crucial role in addressing complex questions in the life sciences. They make it possibly to investigate how life is organised at the molecular level of all proteins. To meet future challenges in speed, sensitivity, and high throughput, the group at Utrecht 木瓜福利影视 recently acquired four new instruments. Each instrument offers unique strengths and opportunities.
Here's a breakdown of the new acquisitions:
This instrument is mainly dedicated to HLA ligandome analyses, a key first step in cancer vaccine development, and for the ultrasensitive analysis of small sample amounts, as needed for single cell proteomics.
Acquired to enhance capabilities in de novo sequencing and glycoproteomics.
Primarily aimed at boosting capabilities in quantitative proteomics, phosphoproteomics, and top-down proteomics.
Coupled with an Orbitrap UHMR, this system enhances capabilities in single molecule mass spectrometry, particularly in analyzing macromolecular complexes.
Breakthrough publication
Collaboration with SpectroSwiss and Thermo Fisher Scientific has already led to a (5 March 2024). The group has achieved a world-record in mass resolution for single ions of macromolecular such as immunocomplexes and nanocages.
Pioneering role
The expansion of the proteomics infrastructure underscores the group's commitment to maintaining a pioneering role in research and development of biomolecular mass spectrometry and proteomics technologies. It also provides access to these facilities locally, nationally, and internationally.
Funding, support, and contact
Funding for this infrastructure expansion (around 3-4 million Euro) is supported by the NWO supported Roadmap Program , the Gravitation programme (ICI), , and the European Infrastructure Program . Additionally, support from the (NWO), Sectorplan BT-II, and Utrecht 木瓜福利影视's Faculty of Science is acknowledged.
These investments highlight Utrecht 木瓜福利影视's dedication to advancing scientific research and fostering collaborations between academia and industry in the field of mass spectrometry and proteomics as enabling technologies for the life sciences.
For more information about the infrastructure and ways to cooperate, please visit the website of the Biomolecular Mass Spectrometry and Proteomics group.