Altertox PBPK Modeling and Quantitative In Vitro-In Vivo Extrapolations

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Physiologically based pharmacokinetic (PBPK) modelling plays a crucial role in next generation (non-animal) risk evaluations to inform the design of in vitro studies and to convert the data obtained with in vitro models into human dose鈭抮esponse or potency information. The goal of the course is to acquaint participants with setting up PBPK models based on non-animal input parameters and to subsequently use these models to extrapolate in vitro bioassay data to human dose-response or potency information. The course is co-organised and hosted at Wageningen 木瓜福利影视.

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Wageningen, The Netherlands
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